TORCH
Toxoplasmosis , other viruses , rubella , cytomegalovirus and herpes simplex virus.
Toxoplasmosis is seen in 1/3 of females exposed by undercooked meat or cat feces .
So, avoid contaminated meat, unwashed fruit/vegetables, unpasteurized cheese, cat feces.
Risks: US demonstrates dilated ventricles, pericardial effusions, echogenic bowel, calcifications in brain.
Rate of transmission
- first trimester is 25%;
- second trimester is 54%;
- third trimester is 75 %.
Rubella: if exposed at least than 11 weeks’ gestation , risk to infant is 90% .
- 11-12 weeks: 33%;
- 13-14 weeks: 11%;
- > 16 weeks: 0%.
Cytomegalovirus
Risks : microcalcifications , microcephaly , MR , IUGR and microcephaly , decreased platelets.
Herpes
Greatest risk to fetus is during primary infection at SVD: 40%. During recurrent infection, infants only are infected <1%.
Varicella – Zoster
Greatest risk on congenital varicella is between 13-20 weeks. No clinical risk after 20 weeks.
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