Condylomata (Genital Warts; HPV)
- Caused by HPV infection of sexually transmitted double-stranded DNA viruses, typically by low-risk types 6, 11;
- Incubation period after exposure ranges from 3 weeks to 8 months;
- Most infections are transiet and cleared within 2 years;
- Viral strains that cause condyloma do not cause cancer;
- May enlarge during pregnancy;
- Usually detected at the time of a Pap smear;
Tests
- Pelvic exam;
- Cervical cytology;
- Colposcopy and biopsy to assess for premalignant lesions (dysplasia);
Labs
- Biopsy specimens at colposcopy;
- HPV viral subtyping as an adjunct to Pap testing may be indicated to assess the concomitant presence of high-risk HPV types;
Treatment
- Chemical or physical destruction;
- Immunologic therapy;
- Surgical excision;
- Spontaneous regression is also possible.
HPV strains causing warts may coexist with strains that cause cervical premalignant changes.
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